Silas' Sphere of Transmutation

So my fellow Alchemists don't have to click back and forth...the BOP Items to craft [item=156631] Drop Locations:

[item=168143] drops from [npc=135474] in [zone=9424]. (Any Difficulty. In M+ contained in end of run Chest)

[item=168146] drops from Priestess Alun'za in [zone=9028]. (Any Difficulty. In M+ contained in end of run Chest)

[item=168144] drops from [npc=133430] & [npc=133432] in [zone=8064]. (Any Difficulty. In M+ contained in end of run Chest)

[item=168145] drops from [npc=127484] in [zone=9327]. (Any Difficulty. In M+ contained in end of run Chest)

I hope this was helpful!

Interacting with the item in your inventory transforms it into different items with different uses.

With the item in my inventory, I found a cauldron. Appeared as a black dot with white outline on minimap. Red smoking cauldrons. Interacting loots random flask or potion (most often a flask). Diminishing returns (rewards got crummier as I hunted for these) so probably not worth farming...just a nice bonus as you're out herbing or world questing.

Some Cauldron Locations: (they appear to be loosely associated with witch mobs or witchy places, which makes sense.)
Near Freehold, Tiragarde Sound at 85.26, 75.67
Fernwood Ridge, Tiragarde Sound at 70.16, 14.00 (by Witch of the Woods)
Algerson Lumber Yard, Tiragarde Sound at 67.80, 18.88 (behind big effigy)
Fletcher's Hollow, Drustvar at 68.65, 63,93
Glenbrook Homestead, Drustvar at 56.20, 38.14
Autumnvale, Drustvar at 57.86, 23,56 (at mouth of cave)
Northpass Caverns, Drustvar at 51.26, 21.68
Upper Corlain, Drustvar at 31.21, 17.31
Corlain, Drustvar at 29.75, 27.58
Corlain Armory at 24.95, 37.18
Crimson Forest, Drustvar 24.57, 56.88

If someone else loots it before you, it will despawn. Respawn timer appears to be about 4-5 minutes.

I find the cost harsh: 50 Anchor Weed and a [item=162519], which in the worst case is another 60 Anchor Weed, in addition to 4 dungeon runs. The engineering one, The Ub3r-Spanner, is significantly cheaper and easier, for instance.