Singular Focus
Damage dealt to targets other than your Marked target deals 5% Plague damage to your Marked target.
Tree position
In the Assassination Rogue talent tree, Singular Focus sits in the Deathstalker hero talent tree, row 2 of 6. It is a single-point node. Its row opens once 1 points are spent in Deathstalker.
Connected above
The tree draws a line into Singular Focus from Deathstalker's Mark.
Deathstalker's MarkGarrote applies 3 stacks of Deathstalker's Mark to your target, unless Deathstalker's Mark is already active. You learn Mark for Death. When you spend 5 or more combo points on attacks against a Marked target you consume an application of Deathstalker's Mark, dealing (156% of Attack Power) Plague damage. Move your active Deathstalker's Mark to your target.
Connected below
Singular Focus leads on to Lingering Darkness or Symbolic Victory.
Lingering DarknessAfter Deathmark expires, gain 30% increased Nature damage for 30 sec.

Same row
Also on this row: Clear the Witnesses, Hunt Them Down and Precise Killer.
Clear the WitnessesFan of Knives damage increased by 60%.
Hunt Them DownAuto-attacks against Marked targets deal an additional (10% of Attack Power) Plague damage.
Precise KillerCritical strike damage bonus increased by 20%.
Talent trees
Singular Focus is in the talent tree of 3 specializations. Rogue: Assassination (DPS), Outlaw (DPS), Subtlety (DPS).
Singular Focus Changes by patch
Tracked changes to this talent between game data builds, newest first.
- First tracked in the game data (patch 12.1.0)