Ultimate Serenity
Increases the healing done by Holy Word: Serenity by 10% and causes it to heal 4 nearby injured allies for 15% of its healing done. Talents that affect Holy Word: Sanctify instead affect Holy Word: Serenity.
Tree position
In the Holy Priest talent tree, Ultimate Serenity sits in the Holy specialization talents, row 8 of 11. It is a single-point node. Its row opens once 20 points are spent in Holy Talents.
Connected above
The tree draws a line into Ultimate Serenity from Apotheosis and Prayers of the Virtuous.
ApotheosisGain a charge of your Holy Words, and enter a pure Holy form for 20 sec, increasing the cooldown reductions to your Holy Words by 200% and reducing their cost by 70%.
Prayers of the VirtuousPrayer of Mending jumps 2 additional times.
Connected below
Ultimate Serenity leads on to Prismatic Echoes and Desperate Times.
Prismatic Echoes2 ranksIncreases the healing done by your Mastery: Echo of Light by 5% and your Renew by 13%.

Same row
Also on this row: Dispersing Light or Trail of Light, Miracle Worker, Eternal Sanctity or Divinity and Say Your Prayers.
Dispersing Light5% of healing done with Flash Heal is replicated to 4 injured allies.
Trail of Light25% of healing done by Flash Heal is replicated to the previous target you healed with those spells.

Eternal SanctityIncreases the duration of Apotheosis by 12 sec.
DivinityYour healing is increased by 10% while Apotheosis is active.
Say Your PrayersPrayer of Mending has a 15% chance to not consume a charge when it jumps to a new target.
Talent trees
Ultimate Serenity is in the talent tree of 3 specializations. Priest: Discipline (Healer), Holy (Healer), Shadow (DPS).
Ultimate Serenity Changes by patch
Tracked changes to this talent between game data builds, newest first.
- Spell changed from 1215275 to 1246517 (patch 12.1.5)
- First tracked in the game data (patch 12.1.0)