Frailty
Enemies struck by Sigil of Flame, Soul Cleave, and Spirit Bomb are afflicted with Frailty for 8 sec. You heal for 10% of all damage you deal to targets with Frailty.
Tree position
In the Vengeance Demon Hunter talent tree, Frailty sits in the Vengeance specialization talents, row 6 of 11. It is a single-point node. Its row opens once 8 points are spent in Vengeance Talents.
Connected above
The tree draws a line into Frailty from Sigil of Spite and Agonizing Flames.
Sigil of SpitePlace a demonic sigil at the target location that activates after 2 sec. Detonates to deal (692% of Attack Power) Chaos damage and shatter up to 3 Soul Fragments from enemies affected by the sigil. Deals reduced damage beyond 5 targets.
Agonizing FlamesImmolation Aura increases your movement speed by 10% and its duration is increased by 50%.
Connected below
Frailty leads on to Void Reaver and Painbringer.
Void ReaverFrailty now also reduces all damage you take from afflicted targets by 6%.

Same row
Also on this row: Feast of Souls, Fallout, Ruinous Bulwark, Volatile Flameblood, Soul Barrier or Soul Sigils and Fel Flame Fortification.
Feast of SoulsSoul Cleave heals for an additional (225% of Attack Power).
FalloutImmolation Aura's initial burst has a chance to shatter Soul Fragments from enemies.
Ruinous BulwarkFel Devastation heals for an additional 10%, and 50% of its healing is converted into an absorb shield for 10 sec.
Volatile FlamebloodImmolation Aura has 10% increased critical strike chance and generates 3-3 Fury when it deals critical damage. This effect may only occur once per 0.1 sec.
Soul BarrierSpirit Bomb shields you for 10 sec, absorbing damage plus for each Soul Fragment consumed.
Soul SigilsAfflicting an enemy with a Sigil generates 1 Soul Fragments.
Fel Flame FortificationYou take 10% reduced magic damage while Immolation Aura is active.
Talent trees
Frailty is in the talent tree of 3 specializations. Demon Hunter: Devourer (DPS), Havoc (DPS), Vengeance (Tank).
Frailty Changes by patch
Tracked changes to this talent between game data builds, newest first.
- First tracked in the game data (patch 12.1.0)