Amplifying Poison
Coats your weapons with a Lethal Poison that lasts for 60 min. Each strike has a chance to poison the enemy, dealing (8.1% of Attack Power) Nature damage and applying Amplifying Poison for 12 sec. Envenom can consume 10 stacks of Amplifying Poison to deal 35% increased damage.
Tree position
In the Assassination Rogue talent tree, Amplifying Poison sits in the Assassination specialization talents, row 7 of 11. It is a single-point node. Its row opens once 8 points are spent in Assassination Talents.
Connected above
The tree draws a line into Amplifying Poison from Sanguine Stratagem, Fatal Concoction and Intent to Kill or Iron Wire.
Sanguine StratagemGain 1 additional max combo point. Your finishing moves that consume more than 5 combo points have increased effects, and your finishing moves deal 5% increased damage.

Intent to KillShadowstep's cooldown is reduced by 33.3333% when used on a target afflicted by your Garrote.
Iron WireGarrotes applied from stealth or during the Improved Garrote window silence their target for 5 sec. Enemies silenced by Garrote deal 15% reduced damage for 5 sec.
Connected below
Amplifying Poison leads on to Dashing Scoundrel and Kingsbane.
Dashing ScoundrelEnvenom's effect also increases the critical strike chance of your weapon poisons by 8%. Your Energy generation is increased by 4% for each lethal poison on your weapons.
KingsbaneRelease a powerful poison from your weapons and inject it into your target, dealing (146.9% of Attack Power) Nature damage instantly and an additional (203% of Attack Power) Nature damage over 14 sec. Each time you apply a Lethal Poison to a target affected by Kingsbane, Kingsbane damage increases by 20%,. Awards 1 combo points.
Same row
Also on this row: Venomous Wounds and Systemic Failure.
Venomous WoundsYou regain 3 Energy each time your Garrote or Rupture deal Bleed damage to a target affected by your weapon poisons. Energy gain is reduced for bleeds beyond the first. If an enemy dies while afflicted by your Rupture, you regain energy based on its remaining duration.
Systemic FailureGarrote increases the damage of Ambush and Mutilate on the target by 30%.
Talent trees
Amplifying Poison is in the talent tree of 3 specializations. Rogue: Assassination (DPS), Outlaw (DPS), Subtlety (DPS).
Amplifying Poison Changes by patch
Tracked changes to this talent between game data builds, newest first.
- First tracked in the game data (patch 12.1.0)
- Spell changed from 381652 to 381664 (patch 12.1.0)