I read through every single comment here and still couldn't figure this out. I didn't understand what on Earth people meant when they said "click the button", "click the crystal", "click the bubble" or "press the correct number".
To start with, position yourself at one of the smaller floating crystals. Rotate your camera so you are looking straight down, zoom in, and move your pet off to one side.
You will see that each of the smaller floating crystals has a large bubble in the center directly under the crystal and four smaller bubbles that form the corners of a square. These smaller bubbles are what you click. They are initially all white, but when you right-click the smaller crystal and activate it they turn faint shades of yellow, red, blue and green. The crystal will make some sounds and flash, then the center bubble will generate a colored spark to the smaller bubble of the same color. You right-click the smaller bubble that the spark goes to, it plays a happy sound, then it starts a second sequence.
The Ogri'Lazy addon is helpful because you can use hotkeys to record the order of the sparks then go back through and click them. Note that you still have to click on the bubbles on the ground. The shortcut keys or macros are only for Ogri'Lazy or whatever other method people are using to keep track of the order. Those do not have anything at all to do with completing the quest.
As a side note, while this is clearly inspired from the old Simon game, it has a significant difference: the pattern resets every time. If Simon started with Yellow, the first color for the rest of your game is Yellow. In this quest the sequence could start with Blue, then the second iteration could start with Yellow. If you were expecting it to build on itself you're in for a surprise.